Vitamin D status predicts new brain magnetic resonance imaging activity in MS

In this 5-year longitudinal MS cohort study from the USA, the authors followed up 469 patients with relapsing-remitting MS on an annual basis and found an inverse relationship between serum vitamin D levels and the risk of developing new T2 lesions on brain MRI. Furthermore each 10ng/ml higher vitamin D level was associated with lower subsequent disability and there was a non-statistically significant trend towards lower relapse rates in patients with higher vitamin D. The authors suggest that these results provide further support for a randomised trial of vitamin D supplementation.

Authors: Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D.

Source: Ann Neurol. 2012 Aug;72(2):234-40. doi: 10.1002/ana.23591.

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