Training in MS: influence of two different endurance training protocols on cytokine and neurotrophin concentrations

In this article from researchers in Switzerland, the authors report on the effects of two endurance exercise regimens in people with MS. Patients were randomised to receive either of the two exercise programmes and were asked to exercise for 30 minutes each day for three weeks.

The data suggest that both exercise programmes produced improvements in cardiorespiratory function in patients. Interestingly, the authors also found that endurance training in water using an aquatic bike may have further beneficial effects on neurotrophin production. They found that patients exercising in water showed a significant increase in brain-derived neurotrophic factor (BDNF) resting and post-exercise concentrations (p<0.05) and that nerve growth factor (NGF) also tended to increase after the training intervention in this group. This is of particular importance in the setting of neurorehabilitation.

Authors: Bansi J, Bloch W, Gamper U, Kesselring J.

Source: Mult Scler. 2012 Aug 30. [Epub ahead of print]

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