Motor and sensory responses after percutaneous tibial nerve stimulation in MS patients with lower urinary tract symptoms

Posterior tibial nerve stimulation (PTNS) is used in the treatment of lower urinary tract symptoms (LUTS) in patients with MS. This study included 83 MS patients with LUTS, unresponsive to medical treatment, who received PTNS for 12 weeks.

The PTNS was carried out after urodynamics to evaluate the prevalence of motor, sensory and combined responses during PTNS and to see if the type of response can predict treatment outcome. A number of questionnaires were also used before and after treatment, to assess LUTS including patient perception of bladder condition (PPBC). A “responder” was defined as someone who reported an improvement of >50% in their LUTS according to the PPBC. Sensory, motor and combined sensory/motor responses were compared between responders and non-responders.

The results from this study showed that 61% of patients were responders. Sensory, motor and combined sensory/motor responses were found in 64%, 6% and 30% of patients respectively. A sensory response alone or in combination with a motor response was associated with a better outcome than the presence of a motor response alone.

Authors: Zecca C, Digesu GA
Source: Eur J Neurol. 2014 Jan 3. doi: 10.1111/ene.12339. [Epub ahead of print]
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