Brain hemodynamic changes associated with chronic cerebrospinal venous insufficiency are not specific to MS and do not increase its severity

In this study from Italy examining the role of chronic cerebrospinal venous insufficiency (CCSVI) in MS, the authors have comprehensively evaluated 39 patients and 26 healthy control subjects using specific colour doppler and cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time assessments with dynamic susceptibility contrast material-enhanced magnetic resonance imaging.

The authors found that although CCSVI was associated with cerebral hemodynamic anomalies, that the changes are equally seen in healthy controls and are not related to severity of disability related to MS.

Authors: Garaci FG, Marziali S, Meschini A, Fornari M, Rossi S, Melis M, Fabiano S, Stefanini M, Simonetti G, Centonze D, Floris R.

Source: Radiology. 2012 Aug 21. [Epub ahead of print]

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